The dysregulation of miRNAs is tightly linked with cancers and tumor microenvironment.19 Bioinformatics analysis suggests that miRNA‐1231 (miR‐1231) binds with the risk variant of LINC00673, conferring the susceptibility to tumorigenesis.20 What is more, miR‐1231 functions as a tumor suppressor with low expression and prognostic significance in glioma and gastric cancer.21, 22, 23 Therefore, the impact of miR‐1231 in exosomes on BM‐MSCs is obscure up to now. The gene discussed is LINC00511; the disease is neoplasm.