Several studies showed that the inhibition of Hh is caused by IPI‐296, which is also known as saridegib.114 As an anti‐FAP monoclonal antibody, unconjugated sibrotuzumab BIBH1 may be a potentially useful immunological‐related antibody to target FAP for the treatment of colon cancer,115 but no complete or partial response was observed in this study. Here, FAP is linked to colonic neoplasm.