Cancer‐associated fibroblasts that were treated with the flavonoid silibinin exhibit lower expression of the MCP‐1 transcription regulators nuclear factor κB (NF‐κB) and AP‐1, consequently decreasing the invasiveness of cancer cells.13, 98 Studies have shown that the overexpression of FAPα promotes the growth and metastasis of tumours. This evidence concerns the gene FAP and neoplasm.