Therefore, it should be considered that a statistical significance found between rs539689 polymorphic site and schizophrenia/suicidal behavior may be due to LD with the tumor necrosis factor-α (TNF-α) SNPs or other adjacent genes (e.g., HLA genes), since TNF gene cluster and HSP70 gene families are at a distance of 600 kb from each other. The gene discussed is TNF; the disease is schizophrenia.