EIF4EBP1 and Familial prostate cancer: Previous studies have revealed that mLST8 was upregulated in human colon and prostate cancer cells (Sapam et al. 2018) and contributed to tumor progression by activating the mTORC1 complex and its effector protein including translation initiation factor 4E-binding protein 1 (4E-BP1) (Yang and Guan.