VEGFA and neoplasm: Various tumor-associated leukocytes including macrophages, neutrophils, myeloid-derived suppressor cells and dendritic cells, mast cells, innate lymphoid cells, γδT cells, and natural killer cells have been identified to not only lead to an immunosuppressive TME but also contribute to angiogenesis by secretion of VEGF, chemokines, cytokines, proteases, structural proteins, and microvesicles [86].