The four modules Antigen Presentation, Immunosuppressive Checkpoints, Danger Signal Module, and Immunostimulatory MiRNA and TF were significantly overexpressed in Anti-tumor Macrophage Group 1 (t-test p values, respectively: <10−4, 0.009, <10−8, <10−5, Fig. 4d) compared to Pro-tumor Macrophage Group 2 (Fig. 4e). This evidence concerns the gene TF and neoplasm.