FLNC and cardiomyopathy: The rare missense variant p.Ala2397Val in FLNC associates with a larger R amplitude in lead V1 and reduced risk of myocardial infarction, with opposite direction of effects to those of p.Phe1626Serfs*40, a reported frameshift variant that causes cardiomyopathy, thus suggesting an opposite functional effect of p.Ala2397Val36.