We found four unreported associations with supraventricular tachycardia (SVT), represented by rs75013985[G] intronic to KCND3 (AF = 2.2%, OR = 1.61, P = 2.7 × 10−9); rs629234[T] upstream of PRRX1 (MAF = 47.9%, OR = 1.11, P = 8.6 × 10−6), which also associates with AF and CAD; rs12144451[C] in CASQ2 (MAF = 43.1%, OR = 0.92, P = 4.4 × 10−4), which also associates with AF; and the missense variant p.Arg935Trp in CCDC141 (MAF = 11.7%, OR = 1.14, P = 7.9 × 10−4). Here, PRRX1 is linked to Supraventricular tachycardia.