HLF and heart failure: We found three associations with complete AV block (CAVB), represented by p.Glu382Asp in CCDC141 (MAF = 15.3%, OR = 1.29, P = 3.6 × 10−7), which also associates with pacemaker insertion (OR = 1.12, P = 5.9 × 10−5) and SSS (OR = 1.13, P = 2.1 × 10−4); rs4794562[T] intronic to HLF (MAF = 25.7%, OR = 0.86, P = 7.8 × 10−4), which also associates with heart failure (OR = 0.95, P = 6.7 × 10−5); and rs17226667[A] near CEP85L (MAF = 45.8%, OR = 1.13, P = 8.1 × 10−4).