REN and gout: In the other articles above, we also noted a variability in the targeted drugs considered at risk of adverse drug reactions (diuretics, anti-gout, renin–angiotensin system inhibitors, antibiotics, oral antidiabetics, digoxin or beta-blockers) (Bhardwaja et al., 2011; Breton et al., 2011; Erler et al., 2012; Geerts et al., 2012; The Royal Dutch Medical Association (KNMG), 2013; Via-Sosa et al., 2013).