For example, dominated with IL-10/TGF-β signal and Treg induction, MDSCs in G-CSF mobilized grafts were different from the MDSCs cells accumulated during GVHD post-HSCT, which were expressing low pSTAT1 (phosphorylated signal transducer and activator of transcription) and high 2,3-IDO [63]. Here, IL10 is linked to graft versus host disease.