In addition to circulating MDSCs in peripheral blood, Bontkes et al. found that high G-MDSCs (CD11b+CD15+CD33int) in the duodenum are associated with enteropathy-associated T cell lymphoma and its precursor lesions, which may contribute to the development of enteropathy-associated T cell lymphoma (EATL) through the suppression of anti-tumor T cell immunity [34]. The gene discussed is ITGAM; the disease is neoplasm.