The high expression of BMI-1 is correlated with poor prognosis so that BMI-1 is considered as a viable therapeutic target in some malignancies, such as colorectal cancer [18, 19], ovarian cancer [20, 21], prostate cancer [22, 23], non-small lung cancer [24], breast cancer [25, 26]. This evidence concerns the gene BMI1 and prostate carcinoma.