HADHA and Fulminant hepatic failure: Previous reports have associated increased plasma levels of 3-hydroxyoctanoate in patients with an inherited deficiency of long-chain 3-hydroxyacyl-CoA dehydrogenase, as a marker of various clinical cases such as recurrent myoglobinuria, hypoketotic hypoglycemic encephalopathy, hypertrophic/dilatative cardiomyopathy, sudden infant death, and fulminant hepatic failure [46, 47].