MiR-128 is downregulated in HCC and suppresses cell proliferation through inducing G1 phase cell arrest via regulating phosphoinositide 3 kinase regulatory subunit 1 (PIK3R1) expression, which inhibits the phosphatidylinositol 3-kinase (PI3K)/AKT signal pathway [152]. The gene discussed is AKT1; the disease is hepatocellular carcinoma.