FOXO3 and hepatocellular carcinoma: MiR-155 additionally inhibits Forkhead box O3 (FoxO3a) expression to suppress downstream apoptotic gene B-cell lymphoma-2 (Bcl-2)-interacting mediator of cell death (BIM) and suppresses cleavage of caspase-3 and caspase-9, consequently inhibiting HCC cell apoptosis and facilitating proliferation [59].