MiR-148-3p was shown to act as an oncogene by promoting prostate cancer cell growth due to repression of its target CAND1 [87], but it was also described as a tumor suppressor, by inhibiting the growth of androgen-refractory PCa cells through repression of mitogen- and stress-activated protein kinase 1 [88]. Here, CAND1 is linked to Familial prostate cancer.