More interestingly, the paper points out that the crosstalk between TAMs and AIP-mutated tumor cells is complex and may rely on an intricate interaction based on the C-C chemokine ligand 5 (CCL5)/C-C chemokine receptor type 5 (CCR5) pathway that appears to be important for the promotion of the invasive character of AIP-mutated GH tumors [43]. The gene discussed is CCR5; the disease is neoplasm.