CD8A and Epstein-Barr virus infection: One likely hypothesis is that active EBV infection exposes KTRs to a broader repertory of EBV epitopes while the expansion of those specific CD8+ T cells is impacted by life-long immunosuppressive treatment; consequently, such balance is traduced in conserved proportions of circulating EBV-specific CD8+ T cells in KTRs, when compared to HCs.