In addition, similar results were revealed for the association between the MMP-8 Lys87Glu variant and cancer risk in allelic contrast (OR = 1.05, 95% CI = 0.93–1.18, P value for heterogeneity = 0.968, P = 0.430); homozygote model (OR = 1.11, 95% CI = 0.88–1.42, Pheterogeneity = 0.953, P = 0.377); heterozygote comparison (OR = 0.96, 95% CI = 0.78–1.18, P value for heterogeneity = 0.647, P = 0.722); dominant model (OR = 1.01, 95% CI = 0.83–1.22, Pheterogeneity = 0.863, P = 0.928), and recessive comparison (OR = 1.13, 95% CI = 0.93–1.38, Pheterogeneity = 0.604, P = 0.222). This evidence concerns the gene MMP8 and cancer.