The AFP-L3%, GALAD score, VEGF, VEGFR-2 levels, as well as the VWF:Ag and VWF:Ag/ADAMTS13:AC ratio, were significantly higher in cirrhotic patients with HCC than in those without HCC (p < 0.01, p < 0.01, p < 0.05, p < 0.01, p < 0.05, and p < 0.01, respectively) (Fig. 1 c, d, e, g, and h). The gene discussed is VWF; the disease is hepatocellular carcinoma.