It was also found that MET signalling is essential for dendritic cell migration through the extracellular matrix, since both MMP‐2 activity and MMP‐9 activity were regulated by this receptor.51 Our results indicate that expression of MET receptor is also crucial for the proteolytic activity of melanoma cells—decreased digestion of fluorescently labelled gelatin and MMP‐9 activity were observed in melanoma cells with diminished level of this protein. The gene discussed is MET; the disease is melanoma.