In addition, a recently identified trans e-QTL (rs5743618) (Quach et al., 2016) in TLR1, a gene with peak Neanderthal introgression (Dannemann et al., 2017; Enard and Petrov, 2018; Hagai et al., 2018; Quach et al., 2016) has been associated to TB susceptibility in several populations worldwide (Barletta-Naveca et al., 2018; Naderi et al., 2016; Qi et al., 2015). This evidence concerns the gene TLR1 and tuberculosis.