BCL2 and pancreatic neoplasm: Researchers have suggested that aspirin can help prevent and treat cancer.15 Several studies have proposed an explanation for the antitumor effect of aspirin, which is given as follows: cell apoptosis by inhibiting Bcl‐2 expression and down regulating cyclooxygenase‐2 expression,16, 17 improving DNA self‐healing,18 and controlling the number of circulating platelets and their activity levels to evade several innate antitumor effects.19 The anticancer effect of aspirin for pancreatic cancer is not clear, because clinical studies on pancreatic cancer have conflicting results.20, 21