SERPINE1 and hemorrhage: Baseline clinical or laboratory characteristics were not significantly different in PAI‐1 5G/5G homozygotes versus PAI‐1 4G carriers except for significantly more post‐lysis hemorrhagic events in PAI‐1 5G/5G homozygotes (frequency of hemorrhage: 19.35% vs. 7% in PAI 5G/5G homozygotes vs. PAI‐1 4G carriers, P = 0.036).