Emerging evidence has indicated that constitutive activation of Wnt/β‐catenin signaling was a major hallmark in various cancers, including HCC.29 Our findings indicate that the miR‐26b/ZNRD1 axis contributes to progression of HCC through regulating the Wnt/β‐catenin signaling. Here, POLR1H is linked to hepatocellular carcinoma.