Notably, these molecules, including SDF1α, are also involved in cell adhesion-mediated drug resistance (CAM-DR) and therefore represent attractive targets for MM therapy (Damiano et al., 1999; Azab et al., 2009; Muz et al., 2015; Waldschmidt et al., 2017). Here, CXCL12 is linked to Miyoshi myopathy.