A study where alveolar macrophages from T2D patients were infected with M. tuberculosis H37Rv, reported reduced levels of expression of CD86, CD80, and HLA-DR, molecules that participate in antigen presentation and Th response; and also a reduced induction of IL-6, IL-1β, IL-10, and IL-12 before and after the infection (Lopez-Lopez et al., 2018). The gene discussed is IL1B; the disease is infection.