These results were further confirmed by analyzing multiple GEO datasets where we found that ADH1A and ALDH2 expression gets upregulated in different HCC cell lines upon treatment with different drugs [Curcumin (55), Vorinostat (56), Resveratrol (57) and Trichostatin A (58)] known to inhibit HDAC1 or its activity. The gene discussed is HDAC1; the disease is hepatocellular carcinoma.