H19 and obesity due to melanocortin 4 receptor deficiency: The functional descriptions in ncRNA2MetS show that imprinted lncRNA H19 increases upon cold-activation and decreases in obesity in BAT (Schmidt et al., 2018); Related studies reveal a previously undescribed double-negative feedback loop between sponge lncRNA and target miRNA that contributes to glucose regulation in muscle cells (Gao et al., 2014); A H19-miR130b pathway regulating lipid metabolism and inflammation response in ox-LDL-treated Raw264.7 cells provides new targets for atherosclerosis treatment (Han et al., 2018).