TPX2 and posterior cortical atrophy: As shown in Fig. 4, high expression of UBE2C, CKS2, CCNB2, HMMR, CDKN3, TPX2 and AURKA showed worse disease-free survival in PCa patients, while the disease-free survival of the other three genes were not significant, which revealed that UBE2C, CCNB2, CKS2, HMMR, CDKN3, TPX2 and AURKA were associated with prostate tumor progression and might be used as tumor progression predictors for prostate tumor patients.