Here, we found that some DMR genes are obesity genes or related to the former which have been studied by genomic and genome-wide association study (GWAS) methods, for example, FTO, PCSK5, PCSK6, NTRK2, ABCC4, TXNIP and RPS6KA2 (Al Muftah et al., 2016; D’Angelo & Koiffmann, 2012; Dina et al., 2007; Milagro et al., 2013). This evidence concerns the gene PCSK5 and obesity due to melanocortin 4 receptor deficiency.