Forkhead box C1 (FOXC1), a hypoxia-induced transcription factor that belongs to the FOX transcription factor family, is upregulated in hypoxic lungs.111–113 Recent studies have reported that miR-200a participates in asthma pathogenesis by targeting FOXC1 through the PI3K/AKT signaling pathway. The gene discussed is AKT1; the disease is asthma.