Altogether, DP2 activation on immune cells leads to the release of IL-4, IL-5, and IL-13, which all have major roles in airway remodeling and structural damage of the pulmonary system.75–77 PGs also play important roles in allergic asthma, and their antagonists can become potent drugs for treating this condition.78 The gene discussed is IL4; the disease is allergic asthma.