CD79A and bacterial infectious disease with sepsis: Intestinal colonization of H. muridarum in mice induces the development of IgA-secreting PCs in the BM, enhancing serum IgA levels and conferring protection against bacterial sepsis.295 Similarly, during the onset of EAE, supplementation of intestinal microbiota that stimulates IgA secretion can facilitate the development of gut-derived IgA+ PC and PB.