DAOA and mood disorder: First, the sample size is still insufficient to reach a more definitive conclusion, and we are not able to include some recent samples from the GWAS data, because the statistical results are not available yet.7,8 Second, our study only focused on seven SNPs in/near the DAOA gene, and further studies should focus on other DAOA SNPs, even rare variants, to evaluate the association between DAOA variation and major mood disorders.