The study conducted on breast cancer tissues by Schiffmann et al. [12] revealed a 12-fold increase in the levels of CERS2 in malignant tissues as compared to normal tissues, while the study conducted by Erez-Roman et al. [30] showed that CERS2 was highly expressed in about half of the invasive ductal carcinoma patients examined. This evidence concerns the gene CERS2 and breast cancer.