To track tumor growth and response to radioimmunotherapy treatment, serum AFP concentration was monitored at 0, 14, and 30 days after administration of either low-dose (200 μCi, n = 9) or high-dose (300 μCi, n = 9) 90Y conjugated to 70 μg of DOTA-αGPC3 via tail vein injection. This evidence concerns the gene AFP and neoplasm.