Interestingly, tumor size also weakly correlated positively with CYP17A1 expression in APA (Supplementary Figure 3A, rs = 0.297, p = 0.03) and there was a trend of a correlation between tumor size and the percentage of cells with a ZF-like cell morphology in APA (rs = 0.242, p = 0.08). Here, CYP17A1 is linked to neoplasm.