The majority of studies documenting the KCNJ5 genotype of APAs reported that patients harboring a KCNJ5 mutant APA were more commonly females, adrenalectomized at a younger age, with a larger tumor size than those harboring a KCNJ5 wild-type APA (18–25, 34, 41). The gene discussed is KCNJ5; the disease is neoplasm.