KRAS and non-small cell lung carcinoma: To investigate the effects of the EGCG derivatives on human NSCLC cell lines, we used three cell lines with different genetic EGFR statuses: A549 (wild-type EGFR), NCI-H441 (wild-type EGFR and KRAS codon 12 mutant), and NCI-H1975 (T790M and L858R point mutations).