To explore the effect of GATA3 on the migration of ccRCC cells, four different ccRCC cell lines, i.e., 786-O, 769-P, ACHN, and Caki-1 cells, were transfected with GATA3 overexpression plasmid or control vector, respectively, and then the cell migration ability was determined by transwell assay. This evidence concerns the gene GATA3 and nonpapillary renal cell carcinoma.