The target genes, whose expression was downregulated in cancer, belong to gene sets such as BREAST CANCER NORMAL LIKE UP, NASOPHARYNGEAL CARCINOMA, DIFFERENTIATING T LYMPHOCYTE, BOUND BY FOXP3, as well as epigenetic related BRAIN HCP WITH H3K4ME3 AND H3K27ME3, ES ICP WITH H3K4ME3, HDAC TARGETS SILENCED BY METHYLATION DN, and many more (Table S4, top). This evidence concerns the gene FOXP3 and cancer.