RUNX1 and metabolic dysfunction-associated steatohepatitis: Furthermore, RUNX1 expression was significantly positively correlated with fibrosis score (r = 0.80, p < 0.001), NAS (r = 0.77, p < 0.001) and inflammatory grade (r = 0.79, p < 0.01) in NASH liver tissues (Figure 2B–D) and therefore correlates with NASH disease severity.