RUNX1 and hepatocellular carcinoma: Performing in vitro cultures, we observed an increased expression of RUNX1 in HUVECs which were treated with CM from PA treated hepatoma cells, indicating that non-saturated fatty acids and/or high fat conditions, which are associated with oxidative stress and generation of reactive oxygen species (ROS), may be inducing RUNX1 expression in HUVECs.