RUNX1 and metabolic dysfunction-associated steatohepatitis: In all the NAFLD samples analyzed in this study, we found RUNX1b as the predominant isoform (data not shown) and therefore, total RUNX1 expression levels correspond to RUNX1b. To analyze the relevance of RUNX1 mRNA expression with regard to disease progress in our patients, its correlation analysis was performed with the histopathological NASH activity score (NAS), the grade of steatosis, as well as inflammation, and the fibrosis score.