Among the confirmed DEGs, we found transcription factor RUNX1, quite recently described to regulate stellate cell activation in NASH [14], and known targets of RUNX1 comprised of CCL2, NOS3 (eNOS), PI3KCA and PRKCE. Intriguingly, among the genes, which were not significantly different among the controls and patient groups, were typical angiogenic genes VEGFA, VEGFR1 and VEGFR2 (Supplementary Table S6). This evidence concerns the gene CCL2 and metabolic dysfunction-associated steatohepatitis.