Recently, Lucena-Araujo et al. in a recent study, proposed the use of an integrative score in APL (ISAPL) based on FLT3-ITD mutational status, ΔNp73/TAp73 expression ratio, ID1, BAALC, ERG and KMT2E gene expression levels. This evidence concerns the gene FLT3 and acute promyelocytic leukemia.