BDNF and Stroke: Moreover, the protein expression of BDNF was also significantly elevated in the brain of recurrent stroke mice after LIPUS treatment (Figure 4B; BDNF: Recurrent-MCAO, 1.10 ± 0.12, Recurrent-MCAO+LIPUS, 2.18 ± 0.28 (fold of control), n = 6, p < 0.05).