Interestingly, previous works have shown that the ectopic expression of cell surface B4GALT1 promotes apoptosis in human hepatocellular carcinoma cells inhibiting EGFR dimerization and tyrosine phosphorylation, indicating that B4GALT1 may be an inhibitor of EGFR signaling [28,29]. This evidence concerns the gene EGFR and hepatocellular carcinoma.