MIF and melanoma: In addition of being implicated in the pathogenesis of autoimmune diseases [7], such as Multiple Sclerosis [10,11,12], Guillain Barrè Syndrome [13] and Type 1 Diabetes [14], MIF has been shown to promote tumorigenesis [15] and it has been described to be overexpressed by various tumors, including mammary [16], colorectal and prostate cancer [17], melanoma [18] and glioblastoma [19,20].