The property of MIF and DDT that enables them to control fundamental cellular processes, such as proliferation and invasion of tumour cells [17], along with the possibility of specific pharmacological inhibition of MIF by small molecules or monoclonal antibody directed against the cytokine or its receptor [7,30,31], has recently focused much attention on the possible use of MIF and DDT as theranostic molecules that may be useful both for diagnostic purposes and as novel chemotherapeutic targets. This evidence concerns the gene MIF and neoplasm.