CXCL8 and non-small cell lung carcinoma: Along the same lines, in non-small cell lung carcinoma, MIF and DDT have been shown to cooperate in regulating angiogenesis, by inducing CXCL8 and VEGF production, and a functional redundancy for MIF and DDT has been also shown in promoting tumor growth and cell migration, in clear renal cell carcinomas [70,71].