We also observed infection-specific downregulation of pathways involved in amino acid biosynthesis and sugar metabolism, and a general switch from expression of sugar transporters to that of amino acid transporters (Figure 3B, Figure 3—source data 2) (with the exception of 4 sugar transporters that were expressed at higher levels in patients: ptsG, fruA, fruB, and gntU. Figure 3—figure supplement 1). This evidence concerns the gene SLC38A7 and infection.