PRDM9 and malaria: The differences observed between the 3D genome organization and virulence gene expression in the primate and rodent malaria parasites are supported by the absence of several proteins involved in epigenetics features in the genome of rodent malaria parasites, such as the histone methyltransferase PfSET2, that have been demonstrated to be critical to monoallelic var gene expression in P falciparum.