For example, for children with a Hb >6g/dl at hospital admission only 520/24372 (2.1%) received a transfusion, and overall 67% of transfusions given were ‘’appropriate’ but this was only judged from admission criteria, the number subsequently developing severe and complicated anaemia, particularly in those with Hb 4-6g/dl admission is unknown. This evidence concerns the gene GSTM1 and anemia (phenotype).