Nonetheless, recent expression and interactome analysis of YB-1 showed that PABP significantly correlated with YB-1 expression in ADC, implying it plays a central role in YB-1 upregulation and highlighting the need for further investigation into the PABP/YB-1 loop (Murugesan et al., 2018). This evidence concerns the gene YBX1 and AIDS dementia complex.