YB-1 has also been implicated in the migration and invasion of breast cancer (Lim et al., 2017), melanoma (Jia et al., 2017), nasopharyngeal cancer (Zhou et al., 2017b), skin squamous cell carcinoma (Wang W. et al., 2004) and spinal chordoma (Liang et al., 2019). This evidence concerns the gene YBX1 and melanoma.