YBX1 and cancer: Although the role of YB-1 has not yet been studied in lung cancer or MPM, it has been shown to be involved in the chemoresistance of many cancers including that of platinum-based chemotherapies (To et al., 2010; Kang et al., 2013; Lasham et al., 2013; Shiota et al., 2014; Yamashita et al., 2017).