On the other hand, in a mouse model of diet induced steatosis, ATG7-deficient T cells show increased expression of IFN ɣ and IL-17 in both CD4+ and CD8+ T cells, suggesting differentiation bias toward Th1 and Th17 phenotypes in CD4+ T cells (Amersfoort et al., 2018). This evidence concerns the gene CD4 and steatosis.