PTEN and neoplasm: Positively correlated with advanced pathological stages, larger tumor sizes, and lymph node metastasis. Knockdown inhibits cell proliferation, induces cell apoptosis and increase G0/G1 cells. DUXAP10 silencing inhibits tumor growth in vivo, also promotes CRC cell growth and reduces cell apoptosis through silencing the expression of p21 and PTEN by binding LSD1