Furthermore, soft tissue sarcomas exhibited low levels of SLFN11 methylation that were independent of CD47 expression (p = 0.27), but had a significant positive correlation between CD47 and SLFN11 expression (p = 4.4 × 10−4), consistent with epigenetic cross-regulation independent of SLFN11 promoter methylation in these tumors. The gene discussed is SLFN11; the disease is soft tissue sarcoma.