GNRH1 and ovarian cancer: EXAMPLES OF USES REPORTED IN CANCER MODELS[D-Lys6]-GnRH-II has potent antiproliferative effect on SKOV-3 human ovarian cancer cell line (61).Cytotoxic conjugate prepared by the attachment of the chemotherapeutical agent daunorubicin to [D-Lys6]-GnRH-II had significantly higher long-term cytotoxic than cytostatic effects in human breast (MCF-7) and colon (HT-29) cancer cell lines (62).