ESR1 and endometrial cancer: EXAMPLES OF USES REPORTED IN CANCER MODELShGnRH-II may be involved in the inhibition of endometrial cancer cell growth (HEC-1A) (59).hGnRH-II can promote apoptosis rate and inhibit cell proliferation of estrogen receptor-negative endometrial cancer cells (HEC-1A) in a dose-dependent manner (60).