On the other hand, in cellular models of human BC such as MCF-7, MDA-MB-231, and T47-D, the administration of [Ac-D2Nal1, D-4Cpa2, D-3Pal3,6, Leu8, D-Ala10]-GnRHII (Table 2) induced the activation of apoptosis and promoted significant inhibition of tumor growth (74, 75). Here, GNRH2 is linked to breast cancer.